1가톨릭대학교 의과대학 대전성모병원 정형외과학교실
Purpose
of study: The purpose of this study is to evaluate the effect of blow flow originated from transverse process after posterolateral lumbar fusion (PLF) in rabbit.
Materials and Methods
Bilateral PLFs using autogenous iliac bone, 3 mm3 on each operated site, were done in 20 rabbits. In group A, PLFs were done on the decorticated transverse processes. In group B, no decortications were done before PLFs. In group C, PLFs were done after application of Bone wax® on the transverse processes. In group D, PLFs were done after application of Surgicel® on the decorticated transverse processes. The five rabbits and 10 operated sites were used in each group. The computed tomography (CT) was done for each group at postoperative 6 and 12 weeks. To evaluate bony union, the status of PLF was divided into ‘union’ and ‘nonunion’ . And, the volumes of grafted bones were counted at each follow up period in each group. The values were analysed statistically.
Results
The union rates of PLFs were observed 90% in group A, 80% in group B, 20% in group C, 70% in group D.
Group C showed lowest union rate than other group with statistical signification (p<0.05). The of volumes of grafted bones at postoperative 6 weeks were calculated to 2.8±0.2 mm3 , 2.6±0.3 mm3 , 1.6±0.8 mm3 , 1.8±0.7 mm3 in group A, B, C, D, retrospectively. At postoperative 12 weeks, the volumes were checked as 2.1±0.6 mm3 , 1.8±0.5 mm3 , 1.2±0.9 mm3 , 1.6±0.4 mm3 in group A, B, C, D, retrospectively. The volumes of grafted bones were checked in order to group A, B, D, and C at 6 and 12 weeks postoperatively. And the volumes in group C were mostly reduced at postoperative 6 and 12 weeks (p<0.05). In group C and D, there were statistically significant reduction in volumes of grafted bones at each follow up period comparing to group A and B (p<0.05).
Conclusions
In the PLF of rabbit, the transverse process-grafted bone contact and blood flow originated from transverse process may play major roles in bony union. Among them, the blood flow originated from transverse process might be more important than the bony contact in the union process of PLF.
