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Original Article

Proximal Junctional Kyphosis and Proximal Junctional Failure Following Adult Spinal Deformity Surgery

Jong-Hwa Park1, Byoung Hun Lee2, Seung-Jae Hyun2, Yongjung J. Kim3, Seung-Chul Rhim4
Journal of Advanced Spine Surgery 2017;7(1):8-17.
Published online: June 30, 2017
1Department of Neurosurgery, Kangdong Sacred Heart Hospital of Hallym University Medical Center, Seoul, Republic of Korea
2Department of Neurosurgery, Spine Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea
3Department of Orthopaedic Surgery, Spine Service, Columbia University College of Physicians and Surgeons, New York, NY
4Department of Neurosurgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
Corresponding author:  Seung-Jae Hyun, Tel: +82-31-787-7164, Fax: +82-31-787-4097, 
Email: hyunsj@snu.ac.kr
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Purpose
The purpose of this review is the current understanding of proximal junctional kyphosis (PJK) and proximal junctional failure (PJF) following adult spinal deformity (ASD) surgery.
Materials and Methods
We carried out a systematic search of PubMed for literatures published up to September 2016 with “proximal junctional kyphosis” and “proximal junctional failure” as search terms. A total of 57 literatures were searched. Finally, the 33 articles were included in this review.
Result
PJK and PJF are recognized complications after long instrumented posterior fusion in ASD surgery. PJK is multifactorial in origin and likely results from surgical, radiographic, and patient related risk factors. PJF is a progressive form of the PJK spectrum including bony fracture of uppermost instrumented vertebra (UIV) or UIV+1, subluxation between UIV and UIV+1, failure of fixation, neurological deficit, which may require revision surgery for proximal extension of fusion. Variable risk factors for PJK and PJF have been investigated, and they can be categorized into surgical, radiographic, and patient-related factors. There are several strategies to minimize PJK and PJF. Soft tissue protections, adequate selection of the UIV, prophylactic rib fixation, hybrid instrumentation such as hooks, vertebral cement augmentation at UIV and UIV+1, and age-appropriate spinopelvic alignment goals are worth consideration.
Conclusion
The ability to perform aggressive global realignment of spinal deformities has also led to the discovery of new complications such as PJK and PJF. Continuous research on PJK and PJF should be proceeded in order to comprehend the pathophysiology of these complications.

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Proximal Junctional Kyphosis and Proximal Junctional Failure Following Adult Spinal Deformity Surgery
J Adv Spine Surg. 2017;7(1):8-17.   Published online June 30, 2017
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Proximal Junctional Kyphosis and Proximal Junctional Failure Following Adult Spinal Deformity Surgery
J Adv Spine Surg. 2017;7(1):8-17.   Published online June 30, 2017
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